Bladder over activity, unless related to
a specific pathology as urinary tract infection or urinary foreign
body and thus should be treated accordingly, is commonly idiopathic.
Either motor or sensor neurological backgrounds are frequently the
underlying cause for the typical symptoms of frequency, urgency, nocturia and urge urinary incontinence that interferes significantly
with the affected patient's quality of life.
Given that OAB (Over Active Bladder) occurrence is as frequent as
both - diabetes and bronchial asthma, is understandable need for effective, free of
side-effects and safe therapy understandable. Previously were
various anti cholinergic and anti muscarinic medications prescribed
for reducing the undesired spontaneous detrusor (bladder muscle)
contractions, but patients drop treatment because of sever side
effects – mainly mouth dryness.
Newly developed bladder specific muscle
relaxing agents are now available upon physician's prescription,
entailing high OAB cure and improved safety.